Kirti K.

Kirti K.

San DiegoCA

GPCR / Oncology In-vitro and In-vivo Research Scientist

• PhD in Pharmacology with more than 14 years of experience in different fields of research, experience in leading multiple projects and train as well as manage research associates • Author to 11 peer reviewed publications • Proficient in drug discovery and small molecule GPCR pharmacology (mechanism and signalling), high throughput screening of small molecules in cell based functional assays. Hand-on experience in Luciferase, cytotoxicity, flow cytometry, confocal microscopy, ELISA, BRET / NanoBit, Ca Flux, Western-blot, pulldown, qPCR assays and APEX based biotinylation technique • Capable of conceiving, developing and execution of methods for in-vitro and in-vivo testing of Antibody Drug Conjugates for oncology indications and identification / validation of new targets for oncology indications • Skilled in tumor cell inoculation, animal dosing via multiple routes (IV, PO, subcutaneous, IP), blood collection, tumor measurements and in-vivo imaging • Molecular biology experience such as cloning using different techniques (Mutagenesis, Gateway cloning, Gibson assembly cloning), qPCR, lentivirus transduction, stable cell line generation • Scientific writing in the area of clinical study reports for bioequivalence studies, protocols, Standard Operating Procedures (SOPs), ICF, CRF and other supporting documents. Also experienced in responding to regulatory agency queries • Excellent communication, time management, organizational and interpersonal skills • Software Knowledge: Windows, MS Office, GraphPad Prism, FlowJo, ImageJ, ICM (Molesoft) for Ligand-receptor Docking, basic knowledge of Python and R-studio • Google scholar: Citations – 128, h-index – 5, i10-index - 5
Kirti K.

Kirti K.

San DiegoCA

GPCR / Oncology In-vitro and In-vivo Research Scientist

Specializes in
• PhD in Pharmacology with more than 14 years of experience in different fields of research, experience in leading multiple projects and train as well as manage research associates • Author to 11 peer reviewed publications • Proficient in drug discovery and small molecule GPCR pharmacology (mechanism and signalling), high throughput screening of small molecules in cell based functional assays. Hand-on experience in Luciferase, cytotoxicity, flow cytometry, confocal microscopy, ELISA, BRET / NanoBit, Ca Flux, Western-blot, pulldown, qPCR assays and APEX based biotinylation technique • Capable of conceiving, developing and execution of methods for in-vitro and in-vivo testing of Antibody Drug Conjugates for oncology indications and identification / validation of new targets for oncology indications • Skilled in tumor cell inoculation, animal dosing via multiple routes (IV, PO, subcutaneous, IP), blood collection, tumor measurements and in-vivo imaging • Molecular biology experience such as cloning using different techniques (Mutagenesis, Gateway cloning, Gibson assembly cloning), qPCR, lentivirus transduction, stable cell line generation • Scientific writing in the area of clinical study reports for bioequivalence studies, protocols, Standard Operating Procedures (SOPs), ICF, CRF and other supporting documents. Also experienced in responding to regulatory agency queries • Excellent communication, time management, organizational and interpersonal skills • Software Knowledge: Windows, MS Office, GraphPad Prism, FlowJo, ImageJ, ICM (Molesoft) for Ligand-receptor Docking, basic knowledge of Python and R-studio • Google scholar: Citations – 128, h-index – 5, i10-index - 5
More than 30 hrs/week