Biotechnology Jobs

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Fixed-Price - Intermediate ($$) - Est. Budget: $100 - Posted
PFA the details. Word-count - 2000 - 3000 The research project is about the Copy Number variation of Carboxylesterase CES1 gene. Gene copy number variation, where different individuals have different numbers of the same gene, is an extensive source of variation between different individuals, with a higher mutation rate than single DNA nucleotides. The extent to which it contributes to disease susceptibility and recent human evolution is unclear. A recent study comparing genomes of different human populations across the world suggested that a copy number variation involving the CES1 (liver carboxylesterase 1) gene shows the largest difference in copy number between different populations. Liver carboxylesterase 1 is involved in the metabolism of cocaine, heroin and several pharmaceutical drugs, including glycovir (an anti-HIV1 drug), aspirin and dabigatran etexilate (an anticoagulant) involved in prevention of stroke in individuals with atrial fibrillation. Liver carboxylesterase 1 is also involved in the invasion of P.falciparum into the liver. Aims & Objectives: 1. Develop a robust molecular genetic assay for CES1 copy number. 2. Predict and investigate the effect of copy number on gene structure and expression. 3. Predict and investigate the duplications between UK Caucasians and find the frequency of duplicated alleles. What I have done? I have designed PRT assays to measure the copy number of CES1 gene. You will find the principle of the PRT in the introduction. I have design two PRT assay including : cis_PRT and trans_PRT. Only cis_PRT has worked and measure the copy number precisely when I applied it on known copy number positive controls. trans_PRT did not work and I excluded it from the experiment. I have run the cis_PRT assay on 5 positive controls and 34 samples from UK Caucasians. I have found that 9 samples from UK Caucasians have duplications as shown in the result. 8 out of 9 have heterozygote duplication alleles, while one have homozygote duplication allele. What I want from you? In the result part, if you could calculate the frequency of duplications between UK Caucasians and also calculate the frequency of heterozygote duplication alleles and the frequency of homozygote duplication allele. If you could apply the Hardy-Weinberg equation to calculate the frequency of those duplications alleles and then write the DISCUSSION PART. Thank you.
Skills: Biotechnology Academic Writing Biology Essay Writing
Fixed-Price - Intermediate ($$) - Est. Budget: $300 - Posted
The topic is on molecular biology, bioengineering, synthetic biology, and microfludics. I will need you to be fluent in the fields above. I will need you to edit paper drafts, as well as researching the topic, write outlines, drafts and also polished versions on this topic. This is not a simple editing job, I will need you to research and write, and extensively communicate with me for the duration of each project. We will discuss payments as we move on to each project. I will need you to sign a NDA at beginning of the contract. This will be an ongoing process, and I am looking for someone who can work with me long-term.
Skills: Biotechnology Academic Writing Biology Editorial Writing
Hourly - Intermediate ($$) - Est. Time: 3 to 6 months, Less than 10 hrs/week - Posted
looking for someone to write articles in medical and technology , I would give you articles and topics , in which you would have to re-write the content and created new articles . you will be ghost writing the info will be posted online re topics I will be submitting you.
Skills: Biotechnology Ghostwriting Medical Writing
Fixed-Price - Intermediate ($$) - Est. Budget: $350 - Posted
We seek a (copy)writer with skills and experience in the pharmaceutical industry ideally with a background on biopharmaceutical analytics. We are a startup company with a unique value proposal and we serve the early value chain of pharmaceutical development. More specifically, with our service and a specialized product portfolio, we support biotech companies to develop pharmaceutical products faster. We believe that the pharmaceutical industry has a rather conservative value chain and we see potential for speeding up the development processes during early drug development. In particular, our products will support smaller biotech companies developing biological generic products, so-called 'Biosimilars' faster. We redefine the early R&D supply chain for biopharma with a new value proposal. Your background should ideally include knowledge of regulatory aspects of biosimilar product registration with regulatory authorities (EMA and FDA). Therapeutic proteins (TP) undergo a complex manufacturing process that varies depending on environmental conditions. As biosimilar products are ‘copy proteins based on an already registered and licensed TP from the original manufacturer (the so-called Reference medicinal product, RMP)’, the copy protein (the biosimilar TP) has to be compared to the RMP using analytical methods to demonstrate the highly similar nature of the biosimilar product. This ‘biosimilar exercise’ is regulated by EMA (EU) and FDA (USA). The white paper should discuss various stages of biosimilar development with a particular focus on biosimilars containing therapeutic monoclonal antibody as the active pharmaceutical ingredient (API). The paper should identify (in the BS guideline) and describe methods for early (comparability) and late (authorization) BS development stages during the analytical, thus, non-clinical ‘biosimilar exercise’. If you feel at home describing these regulatory issues using web research, EMA, FDA, ICH and WHO guidelines, please apply. We are seeking a (White paper) writer with the following skills: • Content writing • B2B writing experience • Case study writing • Good knowledge in regulatory aspects of biosimilar registration process with authority bodies (EMA and FDA) is a major plus. * Knowledge of technical analysis of bioproteins desirable • General understanding for the pharmaceutical industry, with a focus on biotech • Track record of technical, regulatory and/or developmental aspects of biotech products • Knowledge of Good manufacturing practice (GMP) in the pharmaceutical industry is helpful but not required • Knowledge of FDA or EMA are helpful. Biosimilar guidelines can be downloaded from their web sites. • Affinity to detailed writing and research would be great. • 'Easy-to-read' style preferred Note: + Detailed scope document will be supplied + 3-4 fundamental research papers will be provided + links to websites and regulatory institutions will be provided + PDF docs + communication channel: Slack preferred (private channel set up already) + background (white) paper can be provided for + CDA has to be signed in advance before completing Upwork hire process
Skills: Biotechnology Scientific Writing White Paper Writing
Fixed-Price - Entry Level ($) - Est. Budget: $100 - Posted
Hello, I want to submit a patent around a concept of "artificial pregnancy". I need someone with a Biomedical background to work with me and write up the process from a semi realistic medical stand point. This is borderline a joke but i want to get the idea patented. One of those life challenges of "i patented something" If you have experience with biomedical engineering or if you can at least get the idea to the point of patent-ability we can discuss that in the bid process. The price is low as this is borderline technical creative writing. I don't actually expect to make money off this but nearly a joke. You should be able to do a reasonable search to see if the idea is patented yet. I've looked and haven't found anything yet. Again, this is more or less for fun but could at least make a news story or two.
Skills: Biotechnology Biology Human Sciences Intellectual Property Law