Contract Research Lab / Qualified Scientist — Biochemical Enzyme Assays + Mammalian Cell Viability

Posted last month

Worldwide

Summary

I'm seeking an established academic lab, university core facility, or registered contract research organization (CRO) to execute a short, well-defined wet-lab validation study under the supervision of a credentialed scientist. The study supports a structured research project with a fixed, pre-registered experimental design. All experimental design, data analysis, and interpretation are handled on my side; I'm contracting for execution of the bench work and the associated institutional oversight. This is not a project for an individual freelancer working from home. I specifically need a verifiable institutional setting and a named supervising scientist who is willing to be documented as the responsible party for the lab work. Scope of work Biochemical assays: Dose-response activity assays for a small molecule (commercially available, provided/sourced with purity documentation) against a panel of three purified recombinant enzyme targets, using a standard commercial luminescent assay platform. Includes vehicle and positive-control conditions and technical replicates. Cell-based assay: Viability/cytotoxicity dose-response in a standard, documented mammalian cell line (commercial source), using a standard viability assay kit, to establish a non-toxic concentration window. A limited non-viral transfection-based pathway-readout experiment in the same cell line. This is conditional and may be dropped All work is intended to be BSL-1. No hazardous biological agents, no viral vectors, no controlled substances. Final biosafety determination to be confirmed in writing by your institution. What I provide Complete, finalized protocols and plate layouts Compound identity and the comparator to be run alongside The full analysis plan (I do all curve-fitting, statistics, and figures) Pre-registered predictions and go/no-go criteria fixed before work begins Deliverables Raw, unprocessed data files for every assay (plate reader exports, instrument files) plus a methods write-up of exactly what was performed, including lot/catalog numbers, instrument settings, and any deviations from protocol. Documentation of compound identity/purity and cell line source. Written confirmation of the institution's biosafety determination. Willingness of the supervising scientist to be named and to complete standard project documentation truthfully attesting to the work performed and the supervision provided. (Please confirm in your proposal that this is acceptable to you and your institution.) Required qualifications Affiliation with a verifiable university lab, institutional core facility, or registered CRO (please name it) Demonstrated experience with biochemical enzyme-activity assays and mammalian cell culture Ability to provide raw data and full methods detail for independent analysis A named scientist willing to serve as the documented supervisor of record To apply, please include Your institution/facility name and a brief description of your assay capabilities Relevant prior experience with the assay types above timeline Confirmation that you can provide named, documented institutional supervision Confidentiality The specific compound identity, target panel, and analytical framework are confidential and will be shared after we connect, under a mutual NDA. I'm happy to execute an NDA before disclosing protocol-level detail.

  • $200.00

    Fixed-price
  • Entry level
    Experience Level
  • Remote Job
  • Ongoing project
    Project Type
Skills and Expertise
Mandatory skills
Pharmaceutical Industry
Activity on this job
  • Proposals:Less than 5
  • Last viewed by client:4 weeks ago
  • Interviewing:
    1
  • Invites sent:
    2
  • Unanswered invites:
    2
About the client
Member since May 24, 2012
  • United States
    Friendswood2:55 AM
  • $3K total spent
    33 hires, 2 active

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