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Fixed-Price - Intermediate ($$) - Est. Budget: $100 - Posted
PFA the details. Word-count - 2000 - 3000 The research project is about the Copy Number variation of Carboxylesterase CES1 gene. Gene copy number variation, where different individuals have different numbers of the same gene, is an extensive source of variation between different individuals, with a higher mutation rate than single DNA nucleotides. The extent to which it contributes to disease susceptibility and recent human evolution is unclear. A recent study comparing genomes of different human populations across the world suggested that a copy number variation involving the CES1 (liver carboxylesterase 1) gene shows the largest difference in copy number between different populations. Liver carboxylesterase 1 is involved in the metabolism of cocaine, heroin and several pharmaceutical drugs, including glycovir (an anti-HIV1 drug), aspirin and dabigatran etexilate (an anticoagulant) involved in prevention of stroke in individuals with atrial fibrillation. Liver carboxylesterase 1 is also involved in the invasion of P.falciparum into the liver. Aims & Objectives: 1. Develop a robust molecular genetic assay for CES1 copy number. 2. Predict and investigate the effect of copy number on gene structure and expression. 3. Predict and investigate the duplications between UK Caucasians and find the frequency of duplicated alleles. What I have done? I have designed PRT assays to measure the copy number of CES1 gene. You will find the principle of the PRT in the introduction. I have design two PRT assay including : cis_PRT and trans_PRT. Only cis_PRT has worked and measure the copy number precisely when I applied it on known copy number positive controls. trans_PRT did not work and I excluded it from the experiment. I have run the cis_PRT assay on 5 positive controls and 34 samples from UK Caucasians. I have found that 9 samples from UK Caucasians have duplications as shown in the result. 8 out of 9 have heterozygote duplication alleles, while one have homozygote duplication allele. What I want from you? In the result part, if you could calculate the frequency of duplications between UK Caucasians and also calculate the frequency of heterozygote duplication alleles and the frequency of homozygote duplication allele. If you could apply the Hardy-Weinberg equation to calculate the frequency of those duplications alleles and then write the DISCUSSION PART. Thank you.
Skills: Biology Academic Writing Biotechnology Essay Writing
Fixed-Price - Expert ($$$) - Est. Budget: $6 - Posted
Ulatus is currently looking for experienced translators and reviewers to work with us on a freelance basis for our Traditional Chinese <> English translation service. We are currently hiring translators for the following subject areas: 1. Medicine 2. Bio sciences 3. Engineering 4. Agriculture 5. Computer/Information Sciences Freelance translation for Ulatus will enable you to leverage your knowledge in a corporate setup and work with a dedicated, friendly, and interactive team. We provide secure and interactive interface for our freelancer team to work in a flexible environment. We assure, you will find Ulatus as a platform to engage in and enable your passion about effective communication. Eligibility criteria •Proven translation experience is mandatory- minimum 3-year experience in Academic Translation would be preferred. •Native speaker of Traditional Chinese/English with proven English/Traditional Chinese skills •Hold at least a bachelor’s degree in the disciplines mentioned above or related fields •Certification in translation and/or academic translation is preferred •Knowledge of CAT tools will be an add-on In case you are interested, kindly fill our Recruitment Application form - Our freelancers pool consist of experienced professionals who come from rich and diverse background and are master of their subject area’s you can have a look at some of them by visiting To tell you more about us, Crimson Interactive Pvt. Ltd. achieved another milestone by receiving the ISO/IEC 27001:2005 certification for establishing an Information Security Management System (ISMS).Ulatus translation service providing arm of Crimson Interactive Pvt Ltd providing translation solutions to individuals and corporate customers in select few languages – Japanese, English, Traditional Chinese, Portuguese and Indian languages. We have served more than 30,000 clients, translated over 50,000 documents in various languages and are proud to be amongst the top three translation players in Japan. Our Achievements - In 2012, our commitment to excellence in quality gained another international recognition with the World Quality Commitment (WQC) Award in the Gold Category. - 2013, Crimson Interactive won the first prize in “India SME Heroes Challenge.” This nation-wide event was organized by Google and the Federation of Indian Chamber of Commerce and Industry (FICCI). - 2014, Crimson Interactive was honored with the eminent Bizz 2014 award for Business Excellence and Excellence in Quality Management. Some of our clients are: RBS, Sanofi Aventis, Elsevier, Wiley, London School of Economics, Toyota, Tokyo University, Mitsubishi Tanabe amongst many others. We hope you find this opportunity interesting. Thanks & Regards, Rachel Dawson Crimson Interactive Pvt. Ltd.Recruitment Coordinator, Website:,,,
Skills: Biology Computer Engineering Medical Translation
Hourly - Expert ($$$) - Est. Time: Less than 1 month, 30+ hrs/week - Posted
My mother was recently diagnosed with breast cancer, and we as a family are putting together a plan for her treatment. She's seen several doctors, with some recommendations overlapping, and some recommendations conflicting. We are looking for someone with a scientific background to complete research for us into what the science says about each possible treatment modality, including the expected clinical outcomes as well as any risks to paint a complete picture of how we should proceed. For example, one of the common modes of treatment is through a selective estrogen receptor modulator called Tamoxifen, and while it shows some effectiveness in reducing or delaying breast cancer recurrence, there are significantly increased risks of other health complications such as uterine cancer, etc. What we are really trying to do is, based on the available research, create a probabilistic view of what treatments should or shouldn't be pursued. See attached spreadsheet which is our starting point. SKILLS WE'RE LOOKING FOR: We want someone with a scientific background, preferably a PhD, or MD, with experience in scientific research and a strong ability to interpret results of scientific papers and/or find flaws in methods. DELIVERABLES: To get started, we would like to do a 3 way call with you, my mother, and I, to go over everything we are considering doing for her treatment, and the additional research and information we are looking for you to deliver. Time is absolutely essential here for obvious reasons -- we would outline everything required, and would need it delivered within one week from the start date. Expected number of hours required is somewhere in the 50 hour range, but we're not sure yet; you'll have to let us know.
Skills: Biology Data Science Scientific Research
Hourly - Expert ($$$) - Est. Time: More than 6 months, 10-30 hrs/week - Posted
We are looking to hire someone who can help our new fertilizer company get better. We need someone who has a good understanding of nutrient profiles, tissue analysis and how to make the proper adjustments. If there is interest, please send me your skype details so we can discuss the job further. Thank you!
Skills: Biology Botany
Hourly - Entry Level ($) - Est. Time: More than 6 months, 10-30 hrs/week - Posted
For the biomedical or chemistry scientist, with minimum level of BSc, the task of the chemical substance testing, based on the science study literature review in line with the to be provided testing protocol. For the right candidate it will lead to the long term partnership with the potential for exciting carrier and pay rate growth with the first global organisation to challenge status quo of the existing consumer and planet safety regulations. However, it is a new start-up and your expectations for the long term opportunity shall be in synch with the immediate compromise on the pay rate till you prove you are worthy this chance, during the next 6 month probabtion period whilst working on this task. If you want to apply for this job, please confirm, and submit where applicable: 1/ you have the quality of attention to detail, which is paramount to this job; 2/ you may commit at least 10hrs per week or confirm how many maximum hours you may work; 3/ your educational credential proof; 4/ please confirm your lowest pay rate in the view of this job deadlines being quite flexible and bringing the long term partnership, with the rate set to grow once you get selected for this task and in line with the individually set target milestones; 5/ confirm your skype username; 6/ on which week day and at what time you may be online normally on skype for the task full instructions and group training by our mentor. Once you get approved to join our researcher team and work on this task, you will have to sign the NDA agreement (will be forwarded to you in due course). Once you provided the confidentiality agreement, you will be welcomed to join the skype training session to get familiarised with our protocol steps and before conducting the safety tests on your own. You will as well become part of our world changing project. Thank you and we are excited you are to join our team of the international scientists working on half voluntary basis so the human and planet protection changes for the better now.
Skills: Biology Chemistry English
Fixed-Price - Entry Level ($) - Est. Budget: $20 - Posted
I am searching for a writer that can create great content on the topics of health & fitness. The articles must be current up to date , rich content that I can post on a daily to weekly basis. Each article must have at least 500-1000 words and key terms that will help with attracting new followers and encourage my audience to want to read more and enhance ranking in search engines.
Skills: Biology Communications Computer Skills Content Writing